Management of Asymptomatic Severe Hypertriglyceridemia With Oral Therapy Only: A Case Study Shedding Light on Treatment Approaches and Potential Complications

We present a rare case of 52-year-old male with asymptomatic severe hypertriglyceridemia exceeding 11,000 mg/dL, managed initially oral therapy without the need for an insulin drip or plasmapheresis. However, due to non-compliance at home, patient subsequently developed pancreatitis requiring treatment drip. He was discharged on regimen fenofibrate, rosuvastatin, and omega-3, no further episodes symptoms. Asymptomatic patients low risk developing symptoms can be safely through close monitoring, statin, fibrate therapy, lifestyle modifications, but acute persists elevated triglyceride levels over 500 mg/dL marked increase in level greater than 880 mg/dL.